Previous reports on the use of methotrexate have indicated possible help in overcoming the immunity problem in skin and kidney transplants, as well as in bone marrow injections, but problems of timing and quantity of the drug remain to be solved.
Drs. H.L. Lochte Jr., A.S. Levy, D.M. Gunther, E.D. Thomas and J.W. Ferrebee, all of Bassett Hospital, working under a grant from the United States Public Health Service, reported the present study.