DeSimone also scored in the second half, as did teammate Jessica Lyden.
Murphy had eight saves for O-State, which held advantages of 15-13 in shots and 6-4 in corner kicks.
O-State will travel across West Street to play city-rival Hartwick at 7 p.m. Wednesday.
Hartwick 2, Fisher 1
Nicolette Wilson and Cristina Sicari scored less than three minutes apart in the opening half Saturday, leading host Hartwick to an Empire 8 Conference victory that marked its first win over St. John Fisher since 2003.
In the 15th minute, Kylie Thayer took a corner kick that was pushed by Cardinals goalie Brooke Seavitt to Hartwick teammate Angela Luizzi, who passed to Jessica Bentley. Schenevus graduate Bentley touched the ball to Wilson, who followed her initial shot for a rebound goal and a 1-0 lead.
Thayer set up Hartwick’s second goal with a long serve from midfield past the Fisher defense. Sicari, who was named the E8’s Offensive Player of the Week on Monday, turned the play into a one-on-one and beat Seavitt (five saves) inside the 18th minute.
Carly Finn assisted Molly Beaton on Fisher’s goal early in the second half.
Annie Millar made nine saves for the Hawks (7-6-3, 2-3-1), who were outshot, 23-8, by the Cardinals (8-10, 3-3). The Cardinals also had an 11-1 advantage in corner kicks.
Hartwick is tied for fifth place in the E8 with on regular-season game left. SJF is fourth in the E8 but plays first-place Ithaca on Wednesday. The Hawks play Alfred this Saturday, when Elmira meets Stevens. The top four teams advance to the E8 Tournament next month.
LBC 4, Cobleskill 2
Payton Falb scored 1:15 into Sunday’s North Eastern Athletic Conference match for Cobleskill (2-13-1, 2-8-1), which ended its season with a loss at Lancaster Bible College (13-7, 8-3).
Megan Golden, who assisted Falb, gave the Fighting Tigers a 2-0 lead in the ninth minute on a 30-yard free kick, but the Crusaders scored the next four goals.